This 1936 era big metal monster crosses the Illinois River on the west side of the small town of Meredosia. This bridge replaced an earlier wagon bridge. A railroad bridge once crossed the river a few hundred feet downstream from the highway bridge. The Meredosia bridge was reconstructed in 1984. A group of bad floor beams were discovered and fixed in the 1990s.

The bridge was quickly inspected and pronounced to be safe following the I-35W bridge collapse in August, 2007. Despite the bridge being safe, it has a very low sufficiency rating and is eligible for federal funds for replacement. As of late 2007, the Illinois Department of Transportation has earmarked $9-million to begin planning for a replacement bridge.

The city of Meredosia is famous as being one of the first cities in the United States to have a railroad line. The Northern Cross line started in 1838, and was one of the first 3 operating steam railroads in the US. There is a depot and caboose preserved as part of a small museum a few blocks south of IL-104.